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7 Though there aren’t many other studies on sildenafil cream topical for erectile dysfunction, other studies for conditions such as Raynaud’s have demonstrated benefit and increased blood flow as a result of local administration of sildenafil 5% cream, further suggesting that sildenafil may be absorbed from topical administration

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In aged animals models treated with antioxidant agents or hypocaloric diets led to ameliorate in oxidative stress status and tissue function[131,132]